GC-MS Analysis of the Bioactive Compounds N-Hexane Extract of Ramie Leaves and Flowers (Boehmeria nivea) and Antibacterial Test Against Escherichia coli and Klebsiella pneumoniae

Ramie (Boehmeria nivea) is one of the Urticaceae family plants with various potential for pharmacological development. In this study, we analyzed bioactive content n-hexane extract B. nivea leaves and flowers, crude was tested antibacterial activity. The metabolites in flowers ramie were using a Gas Chromatography-Mass Spectrometer (GC-MS). Antibacterial analysis carried out by disc diffusion method at concentrations 20%, 40%, 60%, 80%, 100% inhibiting Escherichia coli Klebsiella pneumoniae. observed based on average result three observations diameter clear zone to determine effectiveness extract. results showed that metabolome data obtained as many 40 compounds. Meanwhile, flower 47 compounds, but compound has not been identified. gave activity 80% against E. an 9.15 ± 0.31 mm 10.29 0.28 mm. contrast, B .nivea did show any confirmation dominant GC-MS consisted tetratetracontane, tetracontane, Stigmast-5-en-3-ol,(3.beta.,24S)-(CAS)Clionasterol, methyl commate D, 2,6,10,14,18,22-Tetracosahexsaene,2,6,10,15,19,23-hexamethyl-, (all-E). recommended other biological activities, such anti-inflammatory, antioxidant, analgesic.